Abstract: There are many influencing factors for calculation of time-depth index. These factors may restrict its application to some extent. In this paper, burial history evolution curve and TDI value have been calculated and compared with actual data considering such influencing factors as decompaction correction, compaction coefficient and initial surface porosity, recovering denudation and overpressure. It can be concluded that the TDI value will be increased while considering decompaction correction. The TDI value of sedimentary layers before the denudation stage will increase while considering recovering denudation. The effective buried depth is smaller than the actual depth in the overpressure environment, and the TDI value will decrease while considering overpressure. The accuracy of the results is affected by the inverted velocity field and the reliability of the relationship between the pressure at well position and velocity.