Abstract: Using Geo-slope geotechnical engineering software,the effective stress method without drainage is applied for the response to earthquake and analysis of liquefaction of Lixigou tailing dam,Jinduicheng.The results show that a .Lixigou tailing dam,Jinduicheng,is stability under static condition; b .the response to acceleration of the tailing dam is less and amplifies 2.204 times; c .the most of dynamic shear stresses and dynamic pore water pressure in the tailing dam increase with the increase of earthquake time; d . the lower pore water pressure and the larger safety coefficient against liquefaction in the tailing dam,but there are local liquefied zone in the tailing dam and will influence dam safe.It suggests that reinforcement may need to prevent from tailing dam failure in the liquefied zone.