Abstract: Aiming at the characteristics of quick lateral changes,strong heterogeneity and difficulty in prediction of He8 lithologic reservoir in Sulige gas field,the study applied AVO analysis of far-near trace stack amplitude and attributes,and pre-stack inversion to the integrated estimation of reservoir lithology and gas-bearing quality based on 2D seismic data.The development appraisal wells from the estimating results have acquired good drilling effects.The methods will improve the prediction reliability of gas charged sands and successful probability of exploitation appraisal wells in low permeability sand reservoir,and will provide instruction to actual work,and will have wide applying foreground.