Abstract: In recent years, the advanced control technology of limestone water hazard in coal seam floor has been widely used as a new technology of limestone water prevention and control. It is characterized by advance in time, wide space range, and good grouting effect. This paper analyzes the basic characteristics of different types of limestone water hazard in coal seam floor in Huainan and Huaibei coalfields, and studies the technical methods and engineering processes for advanced exploration and control of different types of limestone water hazard areas in coal seam floor. For coal mines in the coal seam floor of Huaibei coalfield which is made of multiple thin limestone aquifers with high pressure and abundant water, the directional horizontal drilling technology and the high-density low-pressure filling with low-density high-pressure split grouting technology should be adopted. For the mines in the coal seam floor of Huainan coalfield which is made of incomplete thick aquifuges, the directional horizontal drilling technology and the low density continuous high pressure split grouting technology should be adopted. Through the demonstration of a typical mine project, a good effect of water hazard control has been achieved.