Abstract: This paper, based on a typical soil slopes prototype in Yunnan-Guizhou plateau, designed and completed test on a small vibrostand at scale of 1:6 by using four kinds of acceleration vibration wave input mode. The slope dynamic response characteristics, the deformation and failure law of slope were analyzed by FLAC^3D. The results show that when the input acceleration is below certain threshold, the acceleration response of the whole slope is basic consistent in the same way, and amplification effect at each place does not increase obviously, when the input acceleration increases gradually ans is higher than the critical value, the predominant frequency of slope is fully stimulated and the acceleration response of each place increases, the slope is the most prone to deformation and damage. And the acceleration response has significant amplification effect along the direction of the slope height. The shear strain increment time course curve reflects the fact that in the process of the vibration failure, the trailing edge of the landslide mass is mainly effected by tensioning, the middle and the bottom of the slope are mainly effected by shear, and the variation of shear strain increment at the shear outlet particularly critical, its growth speed directly results in rapid decrease of shear strength. The slope deformation process is divided into four stages, and the failure mode is collapse-shear sliding.