Abstract: According to the zoning characteristics of coal and gas outburst in Pingmei No.10 mine, the method of geological unit division was adopted, reflecting its range of structure characteristics and gas occurrence situation. The characteristics of ground stress distribution in geological unit, structure coal development and gas parameters wrer studied, and combined with outburst feature in the mine, this paper will take gas pressure, coal thickness and gas content as sensitive indicators for predicting coal and gas outburst, and predicted the range of outburst, scientific basis have been provided for the prediction and prevention.